Historically there has been lots of promise about angiogenesis agents however not much to show in terms of practical benefits in a clinically meaningful way. the Dept of Surgery at Grant Medical Center in Columbus Ohio presented their work in a recent JVS Here is an exerpt from EV Today
ADULT STEM CELLS FOR ANGIOGENESIS SHOW PROMISE IN TREATING SEVERE PAD
February 11, 2010—Grant Medical Center in Columbus, Ohio announced that results of a clinical trial documenting the outcomes of nine patients who received transplants of adult stem cells were published by Randall W. Franz, MD, et al in the Journal of Vascular Surgery (2009;50:1378–1390). Few options other than amputation exist for some patients with peripheral arterial disease (PAD) and severe anatomical limitations, the investigators noted.
In this prospective study, the investigators presented short-term results of dual-intramuscular and intra-arterial autologous bone marrow mononuclear cell (BM-MNC) implantation for treating patients with severe PAD for whom amputation was considered the only viable treatment option. Baseline 2-week and 3-month evaluations were
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